ROME – OCTOBER 17: Fans attending the Rome Film Festival premiere of UP IN THE AIR which took place today (Sat 17 Oct) with Jason Reitman, (director Thanks for Smoking & Juno) and George Clooney and Elisabetta Canalis attending during day 3 of the 4th Rome International Film Festival held at the Auditorium Parco della Musica on October 17, 2009 in Rome, Italy. (Photo by Vittorio Zunino Celotto/Getty Images)